Production of outer surface protein A byBorrelia burgdorferiduring transmission from infected mammals to feeding ticks is insufficient to trigger OspA seroconversion
نویسندگان
چکیده
منابع مشابه
ProductionofoutersurfaceproteinAbyBorreliaburgdorferi during transmission from infectedmammals to feeding ticks is insu⁄cient to triggerOspA seroconversion
The Lyme disease spirochete, Borrelia burgdorferi, produces two outer surface lipoproteins, OspA and OspB, that are essential for colonization of tick vectors. Both proteins are highly expressed during transmission from infected mammals to feeding ticks and during colonization of tick midguts, but are repressed when bacteria are transmitted from ticks to mammals. Humans and other infected mamma...
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The Lyme disease-associated spirochete, Borrelia burgdorferi, is maintained in enzootic cycles involving Ixodes ticks and small mammals. Previous studies demonstrated that B. burgdorferi expresses outer surface protein A (OspA) but not OspC when residing in the midgut of unfed ticks. However, after ticks feed on blood, some spirochetes stop making OspA and express OspC. Our current work examine...
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ژورنال
عنوان ژورنال: FEMS Immunology & Medical Microbiology
سال: 2008
ISSN: 0928-8244,1574-695X
DOI: 10.1111/j.1574-695x.2008.00473.x